Funding landscape for new antibacterials

๐€๐ง๐ญ๐ข๐›๐š๐œ๐ญ๐ž๐ซ๐ข๐š๐ฅ ๐ฆ๐ž๐๐ข๐œ๐ข๐ง๐ž๐ฌ ๐œ๐š๐ง ๐ฌ๐š๐ฏ๐ž ๐ฅ๐ข๐ฏ๐ž๐ฌ. ๐๐ฎ๐ญ ๐๐จ ๐ฐ๐ž ๐ค๐ง๐จ๐ฐ ๐ก๐จ๐ฐ ๐ญ๐ก๐ž๐ฒ ๐š๐ซ๐ž ๐Ÿ๐ฎ๐ง๐๐ž๐ – ๐š๐ง๐ ๐ฐ๐ก๐š๐ญ ๐ง๐ž๐ž๐๐ฌ ๐ญ๐จ ๐œ๐ก๐š๐ง๐ ๐ž ๐ญ๐จ ๐›๐ž๐ญ๐ญ๐ž๐ซ ๐ฌ๐ฎ๐ฉ๐ฉ๐จ๐ซ๐ญ ๐ญ๐ก๐ž๐ข๐ซ ๐๐ž๐ฏ๐ž๐ฅ๐จ๐ฉ๐ฆ๐ž๐ง๐ญ?

Weโ€™re very happy to share that our new paper โ€œ๐˜ˆ๐˜ฏ ๐˜ฐ๐˜ท๐˜ฆ๐˜ณ๐˜ท๐˜ช๐˜ฆ๐˜ธ ๐˜ฐ๐˜ง ๐˜จ๐˜ญ๐˜ฐ๐˜ฃ๐˜ข๐˜ญ ๐˜ฑ๐˜ถ๐˜ฃ๐˜ญ๐˜ช๐˜ค ๐˜ข๐˜ฏ๐˜ฅ ๐˜ฑ๐˜ฉ๐˜ช๐˜ญ๐˜ข๐˜ฏ๐˜ต๐˜ฉ๐˜ณ๐˜ฐ๐˜ฑ๐˜ช๐˜ค ๐˜ช๐˜ฏ๐˜ท๐˜ฆ๐˜ด๐˜ต๐˜ฎ๐˜ฆ๐˜ฏ๐˜ต๐˜ด ๐˜ช๐˜ฏ๐˜ต๐˜ฐ ๐˜ข๐˜ฏ๐˜ต๐˜ช๐˜ฃ๐˜ข๐˜ค๐˜ต๐˜ฆ๐˜ณ๐˜ช๐˜ข๐˜ญ ๐˜ต๐˜ฉ๐˜ฆ๐˜ณ๐˜ข๐˜ฑ๐˜ฆ๐˜ถ๐˜ต๐˜ช๐˜ค๐˜ด (2017โ€“23)โ€, has just been published in the ๐‹๐š๐ง๐œ๐ž๐ญ ๐Œ๐ข๐œ๐ซ๐จ๐›๐ž!

๐–๐ก๐š๐ญ ๐๐ข๐ ๐ฐ๐ž ๐Ÿ๐ข๐ง๐?
ยทย ย ย ย ย ย Investment peaked in 2020 and has since fallen by 18%

ยทย ย ย ย ย  $2.51 billion was invested by 130 funders, with funding highly concentrated among a few major players

ยทย ย ย ย ย ย Early-research funding has declined, while clinical development remains relatively stable

ยทย ย ย ย ย ย Funding broadly aligns with WHO priority pathogens, though some gaps remain

ยทย ย ย ย ย ย Traditional approaches dominate, while many non-traditional strategies, like phages, peptides etc., struggle to translate

๐–๐ก๐ฒ ๐ญ๐ก๐ข๐ฌ ๐ฆ๐š๐ญ๐ญ๐ž๐ซ๐ฌ
As private investment continues to shrink, antibacterial innovation increasingly relies on public funding, philanthropy, and partnerships

Initiatives such as Global Antibiotic R&D Partnership (GARDP) and CARB-X are essential – but they alone cannot sustain the system

๐Ž๐ฎ๐ซ ๐ญ๐š๐ค๐ž-๐ก๐จ๐ฆ๐ž ๐ฆ๐ž๐ฌ๐ฌ๐š๐ ๐ž
Sustained investment is necessary, but stronger strategic alignment across funders, sectors, and R&D stages is essential to deliver new antibacterial medicines that meet priority public health needs

This work is the result of a close collaboration between Global Antibiotic R&D Partnership (GARDP) and the Global AMR R&D Hub.


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