One Health Lens for Antimicrobial Resistance Research and Funding: A Systematic Review

A collaborative paper by Issam Alsamara and Prof. Angela Brand from Maastricht University together with the Global AMR R&D Hub presents a systematic review on the One Health funding landscape for cross-sectoral antimicrobial resistance (AMR) research and development, and its alignment and gaps with the current global strategic agenda on AMR. To the best of the authors’ knowledge, this is the first study that systematically reviews the cross-sectoral literature on AMR, classifies it, and aligns and contextualises it in regard to the AMR funding landscape. 777 studies and reviews on AMR encompassing more than one One Health sector were included covering the period between January 2015 and May 2022. Of the 777 included studies, 475 (61%) covered all three One Health sectors.

Key points:

  • The environment was the most neglected sector in the One Health triad (human health, animal health, environmental health).
  • AMR surveillance, transmission, and interventions are the most commonly studied priority topics, while diagnosis and therapeutics are underrepresented in One Health AMR research.
  • Both cross-sectoral AMR literature and investments have been increasing since 2017.

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